| Company
Name: University of Bath |
| Job
Location: Bath |
| Job
Status: Full Time |
Job
Description :
Applications are invited for the post of Research Assistant in Wound Healing and Tissue Repair based in the Department of Biology & Biochemistry at the University of Bath, one of the UK’s most prestigious universities. You will undertake research in a vibrant research environment with an excellent international reputation.
This post has arisen as a result of the award of a Wellcome Trust/Royal Society Sir Henry Dale Fellowship to Dr. David Gurevich and is essential to a programme of work to understand the regulation of inflammation and angiogenesis during wound healing, and how these fail in the context of compromised wounds such as those that develop in diabetes.
The successful applicant will have a central role in delivering on this programme of research that aims to unravel the mechanisms underlying crucial tissue repair responses, as well as being part of a growing, multidisciplinary and collaborative research community.
You will be responsible for experimental aspects of the project, principally applying a combination of cutting edge molecular and genetic techniques (including single cell transcriptomics, CRISPR gene editing, generating new transgenic reporter lines) with live in vivo microscopy of zebrafish to determine immune cell-endothelial cell interactions, investigating how key genes and pathways drive tissue revascularisation during repair and how this process breaks down in compromised diabetic wounds.
Building on previous multi-model work (Gurevich et al, 2018, EMBOJ, e97786, DOI: 10.15252/embj.201797786), you will complement these zebrafish investigations with an in vitro human immune cell/endothelial cell co-culture assay, validating the mechanistic findings from the fish studies on patient samples.
This vital work will inspire and drive appropriate follow-up experiments, and ultimately aid in facilitating the development of novel therapies and clinical practice.
A degree in biological or biomedical science is essential for the successful candidate, as is previous research experience subsequent to graduation. Experience in genetic manipulation (e.g. CRISPR, transgenesis) and experience in bench work and molecular biology techniques (e.g. PCR, cloning, DNA/RNA extraction) is also essential.
Experience in working with zebrafish, in vitro work with human tissue culture models, and analysis of large datasets (e.g. transcriptomics, proteomics) are highly desirable. Excellent microscopy and imaging skills (both live and fixed samples), experience in fluorescent activated cell sorting (FACS), flow cytometry and immunohistochemistry are also desirable. You must be highly organised and have excellent laboratory organisational and communication skills as the post would include laboratory management duties alongside a research role. An ability to work well in a team, supervise and train colleagues and work independently will also be crucial.
This is a full-time post for a fixed term of up to 4 years.
For an informal chat about the role please contact Dr David Gurevich at dbg29@bath.ac.uk.
We recognise the commitment, achievements and talents of our workforce through our offering of initiatives and benefits, including (but not limited to):
- Generous employer pension contributions
- 39 days holiday (annual leave, discretionary days and bank holidays)
- A flexible working environment
- A commitment to personal and professional development
- Ofsted outstanding rated onsite nursery
- Salary exchange scheme (cycle to work)
- Onsite private and NHS dentist, onsite medical centre
- Employee discount scheme
Our campus is surrounded by beautiful countryside, and the City of Bath with its historic charm and social activity only a short distance away creates an excellent environment in which to work.
We are a family friendly workplace and are open to exploring flexible working opportunities which benefit you and the University. We recognise the talents of our diverse workforce through an excellent reward package including a generous pension scheme and annual leave entitlement and are encouraging of your personal and professional development.
Find out from our staff what makes the University of Bath a great place to work. Follow us @UniofBath and @UniofBathJobs on Twitter for more information.
We aim to be an inclusive university, where difference is celebrated, respected and encouraged. We truly believe that diversity of experience, perspectives, and backgrounds leads to a better environment for our employees and students, creating a learning environment and organisational culture that enhances health and wellbeing across our community. We are very proud to have recently received Ambassadors for Autism certification and are an accredited Disability Confident Leader; committed to building disability confidence and supporting disabled staff. |
Job Requirements/
Application Instructions:
Visit https://www.bath.ac.uk/jobs/CC8037 to complete an application
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| Salary:
Dr David Gurevich26715 |
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| Contact: |
| Phone: 32817 |
| Link: https://www.bath.ac.uk/jobs/CC8037http://www. |
| Address: |
Dr David Gurevich
University of Bath
University of Bath, Claverton Down, Bath
Bath
BA Bath
BA2 7AY |
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